Last update 06 Jun 2025

TTP-4000

Overview

Basic Info

Drug Type
Fusion protein
Synonyms
TTP 4000, TTP4000
Target
AGER
Action
antagonists
Mechanism
AGER antagonists(Advanced glycosylation end product-specific receptor antagonists)
Therapeutic Areas
Nervous System DiseasesOther Diseases
Active Indication-
Inactive Indication
Alzheimer DiseaseCognitive Dysfunction
Originator Organization
vTv Therapeutics, Inc.vTv Therapeutics, Inc.
Active Organization-
Inactive Organization
vTv Therapeutics, Inc.vTv Therapeutics, Inc.
License Organization
Pfizer Inc.Pfizer Inc.vTv Therapeutics, Inc.vTv Therapeutics, Inc.
Drug Highest PhasePendingPhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with TTP-4000
NCT01548430
/ CompletedPhase 1
A Double-blind, Randomized, Placebo-controlled, Phase 1 Study of 2 Escalating, Single Subcutaneous Doses to Evaluate the Safety, Tolerability, Immunogenicity, and Pharmacokinetics of TTP4000 in Subjects With Alzheimer's Disease With Mild Cognitive Impairment
100 Clinical Results associated with TTP-4000
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100 Translational Medicine associated with TTP-4000
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100 Patents (Medical) associated with TTP-4000
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100 Deals associated with TTP-4000
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Alzheimer DiseasePhase 1
United States
vTv Therapeutics, Inc.vTv Therapeutics, Inc.
01 Oct 2011
Cognitive DysfunctionPhase 1
United States
vTv Therapeutics, Inc.vTv Therapeutics, Inc.
01 Oct 2011
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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