Last update 13 Dec 2025

HRS-4508

Overview

Basic Info

Drug Type
Chemical drugs
Synonyms
HRS-4508
Target
HER2
Action
antagonists
Mechanism
HER2 antagonists(Receptor tyrosine-protein kinase erbB-2 antagonists)
Therapeutic Areas
NeoplasmsRespiratory Diseases
Active Indication
Locally Advanced Lung Non-Small Cell CarcinomaAdvanced Malignant Solid NeoplasmMetastatic Solid Tumor
Inactive Indication-
Originator Organization
Jiangsu Hengrui Pharmaceuticals Co., Ltd.Jiangsu Hengrui Pharmaceuticals Co., Ltd.
Active Organization
Jiangsu Hengrui Pharmaceuticals Co., Ltd.Jiangsu Hengrui Pharmaceuticals Co., Ltd.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Related

7
Clinical Trials associated with HRS-4508
NCT07232849
/ Not yet recruitingPhase 2
Study on Efficacy and Safety of HRS-4508 Combined With Other Antitumor Therapies in Subjects With Locally Advanced or Metastatic Non-small Cell Lung Cancer
CTR20254157
/ RecruitingPhase 2
HRS-4508联合其他抗肿瘤治疗在非小细胞肺癌受试者中的安全性、耐受性及有效性的开放、多中心的II期临床研究
[Translation] An open-label, multicenter Phase II clinical study of the safety, tolerability, and efficacy of HRS-4508 combined with other anti-tumor therapies in subjects with non-small cell lung cancer
NCT07140393
/ Not yet recruitingPhase 1/2
An Open, Multicenter Phase IB/II Clinical Study of HRS-4508 in Combination With Other Anti-tumor Therapy for Solid Tumor
100 Clinical Results associated with HRS-4508
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100 Translational Medicine associated with HRS-4508
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100 Patents (Medical) associated with HRS-4508
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100 Deals associated with HRS-4508
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Locally Advanced Lung Non-Small Cell CarcinomaPhase 2
China
Jiangsu Hengrui Pharmaceuticals Co., Ltd.Jiangsu Hengrui Pharmaceuticals Co., Ltd.
12 Sep 2025
Advanced Malignant Solid NeoplasmPhase 1
China
Jiangsu Hengrui Pharmaceuticals Co., Ltd.Jiangsu Hengrui Pharmaceuticals Co., Ltd.
30 Sep 2024
Metastatic Solid TumorPhase 1
China
Jiangsu Hengrui Pharmaceuticals Co., Ltd.Jiangsu Hengrui Pharmaceuticals Co., Ltd.
30 Sep 2024
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Clinical Result

Indication
Phase
Evaluation
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Clinical Trial

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Approval

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Regulation

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