Last update 29 Jul 2025

AAV-delivered DWORF gene therapy (Tenaya Therapeutics)

Overview

Basic Info

Drug Type
AAV based gene therapy
Synonyms-
Target
DWORF
Action
modulators
Mechanism
DWORF modulators(small transmembrane regulator of ion transport 1 modulators)
Therapeutic Areas
Cardiovascular DiseasesOther Diseases
Active Indication
Cardiomyopathy, DilatedHeart failure with reduced ejection fractionCardiomyopathies+ [1]
Inactive Indication-
Originator Organization
Tenaya Therapeutics, Inc.Tenaya Therapeutics, Inc.
Active Organization
Tenaya Therapeutics, Inc.Tenaya Therapeutics, Inc.
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with AAV-delivered DWORF gene therapy (Tenaya Therapeutics)
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100 Translational Medicine associated with AAV-delivered DWORF gene therapy (Tenaya Therapeutics)
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100 Patents (Medical) associated with AAV-delivered DWORF gene therapy (Tenaya Therapeutics)
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100 Deals associated with AAV-delivered DWORF gene therapy (Tenaya Therapeutics)
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Cardiomyopathy, DilatedPreclinical-
Tenaya Therapeutics, Inc.Tenaya Therapeutics, Inc.
23 Jan 2024
Heart failure with reduced ejection fractionPreclinical-
Tenaya Therapeutics, Inc.Tenaya Therapeutics, Inc.
23 Jan 2024
CardiomyopathiesPreclinical
United States
Tenaya Therapeutics, Inc.Tenaya Therapeutics, Inc.
-
Heart FailurePreclinical
United States
Tenaya Therapeutics, Inc.Tenaya Therapeutics, Inc.
-
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Clinical Result

Indication
Phase
Evaluation
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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