Last update 08 May 2025

BF-114

Overview

Basic Info

Drug Type
siRNA
Synonyms-
Target
SPTBN1
Action
inhibitors
Mechanism
SPTBN1 inhibitors(spectrin beta, non-erythrocytic 1 inhibitors)
Therapeutic Areas
NeoplasmsDigestive System DisordersEndocrinology and Metabolic Disease
Active Indication
Hepatocellular CarcinomaMetabolic dysfunction-associated steatotic liver diseaseObesity+ [1]
Inactive Indication-
Originator Organization
Bullfrog International LCBullfrog International LC
Active Organization
Bullfrog International LCBullfrog International LCBullFrog AI Holdings, Inc.
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Structure/Sequence

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Related

100 Clinical Results associated with BF-114
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100 Translational Medicine associated with BF-114
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100 Patents (Medical) associated with BF-114
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100 Deals associated with BF-114
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Hepatocellular CarcinomaPreclinical
United States
Bullfrog International LCBullfrog International LC
-
Metabolic dysfunction-associated steatotic liver diseasePreclinical
United States
Bullfrog International LCBullfrog International LC
-
ObesityPreclinical
United States
Bullfrog International LCBullfrog International LC
-
Nonalcoholic SteatohepatitisDiscovery
United States
BullFrog AI Holdings, Inc.
22 Aug 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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