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Clinical Trials associated with JL-15003 / Not yet recruitingPhase 1 评估JL15003注射液治疗复发胶质母细胞瘤(rGBM)患者的安全性、有效性的Ib/Ⅱ 期临床试验
[Translation] Phase Ib/II clinical trial to evaluate the safety and efficacy of JL15003 injection in the treatment of patients with recurrent glioblastoma (rGBM)
主要目的: 评价JL15003注射液按需给药治疗rGBM患者的安全性。
次要目的: 初步评价JL15003注射液按需给药治疗rGBM患者的有效性; 评估JL15003注射液按需给药的病毒脱落情况。
探索性目的: 探索与JL15003注射液相关的生物标志物。
[Translation] Primary objective: To evaluate the safety of JL15003 injection for the treatment of rGBM patients on demand.
Secondary objective: To preliminarily evaluate the efficacy of JL15003 injection for the treatment of rGBM patients on demand; To evaluate the viral shedding of JL15003 injection for on-demand administration.
Exploratory objective: To explore biomarkers associated with JL15003 injection.
JL15003注射液治疗复发胶质母细胞瘤患者的安全性和耐受性临床研究
[Translation] Clinical study on the safety and tolerability of JL15003 injection in the treatment of patients with recurrent glioblastoma
主要目的:
评价JL15003注射液治疗复发胶质母细胞瘤患者的安全性和耐受性。
次要目的:
初步评价JL15003对复发胶质母细胞瘤患者的疗效,为II期临床试验的给药剂量提供依据;
观察JL15003在瘤内给药后的病毒脱落情况;
探索复发胶质母细胞瘤患者肿瘤组织中与JL15003疗效相关的生物标志物。
[Translation] Main purpose:
Evaluate the safety and tolerability of JL15003 injection in the treatment of patients with recurrent glioblastoma.
Secondary purpose:
Preliminary evaluation of the efficacy of JL15003 in patients with recurrent glioblastoma, and provide a basis for the dosing of Phase II clinical trials;
Observe the viral shedding of JL15003 after intratumoral administration;
Explore biomarkers related to the efficacy of JL15003 in tumor tissues of patients with recurrent glioblastoma.
100 Clinical Results associated with JL-15003
100 Translational Medicine associated with JL-15003
100 Patents (Medical) associated with JL-15003
100 Deals associated with JL-15003