Last update 04 Mar 2026

KC-128

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
KC-128
Target
Kv7.2
Action
agonists
Mechanism
Kv7.2 agonists(Voltage-gated potassium channel subunit Kv7.2 agonists)
Therapeutic Areas
Nervous System DiseasesCardiovascular DiseasesOther Diseases
Active Indication-
Inactive Indication
Angina PectorisHypertension
Originator Organization
Chugai Pharmaceutical Co., Ltd.Chugai Pharmaceutical Co., Ltd.
Active Organization-
Inactive Organization
Chugai Pharmaceutical Co., Ltd.Chugai Pharmaceutical Co., Ltd.
License Organization-
Drug Highest PhasePendingDiscovery
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC15H16N4O3
InChIKeyGCEOZHFFNHJZTB-UHFFFAOYSA-N
CAS Registry141591-92-6

Related

100 Clinical Results associated with KC-128
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100 Translational Medicine associated with KC-128
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100 Patents (Medical) associated with KC-128
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2
Literatures (Medical) associated with KC-128
01 Aug 1994BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Substituent effects of benzopyran-4-(N-cyano)-carboxamidine potassium channel openers for selectivity to guinea pig trachealis
01 Jun 1993BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
N,N-disubstituted benzopyran-4-(N′-cyano)carboxamidines, cromakalim analogs with selective activity for guinea pig trachealis
100 Deals associated with KC-128
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Angina PectorisDiscovery
Japan
Chugai Pharmaceutical Co., Ltd.Chugai Pharmaceutical Co., Ltd.
-
HypertensionDiscovery
Japan
Chugai Pharmaceutical Co., Ltd.Chugai Pharmaceutical Co., Ltd.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Clinical Trial

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Approval

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Regulation

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