Last update 08 May 2025

Aspirin/Caffeine/Acetaminophen

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms-
Target
A1R x A2aR x COXs
Action
antagonists, inhibitors
Mechanism
A1R antagonists(Adenosine A1 receptor antagonists), A2aR antagonists(Adenosine A2a receptor antagonists), COX inhibitors(Cyclooxygenases inhibitors)
Therapeutic Areas
Nervous System DiseasesOther Diseases
Active Indication
Migraine DisordersAnesthesia
Inactive Indication-
Originator Organization
GlaxoSmithKline Consumer Healthcare Ltd.
Active Organization
Haleon US Capital LLC
Inactive Organization-
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (14 Jan 1998),
Migraine Disorders
Regulation-
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Structure/Sequence

Molecular FormulaC8H10N4O2
InChIKeyRYYVLZVUVIJVGH-UHFFFAOYSA-N
CAS Registry58-08-2
View All Structures (3)

Related

1
Clinical Trials associated with Aspirin/Caffeine/Acetaminophen
NCT01629329
/ TerminatedPhase 4IIT
A Randomized, Double-blind Comparison of Single Dose Prochlorperazine Versus Acetaminophen, Aspirin and Caffeine for the Treatment of Acute Migraine in the Emergency Department.
100 Clinical Results associated with Aspirin/Caffeine/Acetaminophen
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100 Translational Medicine associated with Aspirin/Caffeine/Acetaminophen
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100 Patents (Medical) associated with Aspirin/Caffeine/Acetaminophen
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100 Deals associated with Aspirin/Caffeine/Acetaminophen
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External Link

KEGGWikiATCDrug Bank
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N01
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R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Migraine Disorders
United States
Haleon US Capital LLC
14 Jan 1998
Anesthesia
China
--
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
NCT01629329 (Migraine, CTgov)
Phase 4
Acute migraine
93
(Aspirin, Acetaminophen, Caffeine Pills)
nxuwhbtnxr(bhjylovgxd) = safevcksgd nydrdvxyse (dguicnvlpd, rggjpefxgh - icwwvxhoxd)
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-
18 Mar 2020
(Prochlorperazine 10mg)
nxuwhbtnxr(bhjylovgxd) = ycygtxzqeu nydrdvxyse (dguicnvlpd, adsvwliqfx - uhadyzkjmq)
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Clinical Trial

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Approval

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Regulation

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