TRPA1 agonists(Transient receptor potential cation channel subfamily A member 1 agonists), TRPM8 agonists(Transient receptor potential cation channel subfamily M member 8 agonists)

Therapeutic Areas

Nervous System Diseases

Active Indication

Pain

Inactive Indication-

Originator Organization

Hisamitsu Pharmaceutical Co., Inc.

Active Organization

Hisamitsu Pharmaceutical Co., Inc.

Inactive Organization-

Drug Highest PhaseApproved

First Approval Date

US (20 Feb 2008),

Pain

Regulation-

Structure

Molecular FormulaC8H8O3

InChIKeyOSWPMRLSEDHDFF-UHFFFAOYSA-N

CAS Registry119-36-8

View All Structures (2)

Clinical Trials associated with Menthol/Methyl Salicylate

NCT05106400 / CompletedPhase 1

Open-label, Randomized, Four-treatment, Four-sequence, Four-period, Crossover, Single-application Study Evaluating and Comparing Product Adhesion in Healthy Adult Subjects Using ZTlido 1.8% Versus Salonpas(Lidocaine Patch 4%), Aspercreme(Lidocaine Patch 4%) and IcyHot(Lidocaine 4% + Menthol 1% Patch)

The study is designed to evaluate and compare the clinical adhesion performance of the ZTlido (Lidocaine Topical System) 1.8% of Scilex Pharmaceuticals Inc. (Reference) versus Salonpas (Lidocaine Patch 4%), Aspercreme (Lidocaine Patch 4%) and IcyHot (Lidocaine 4% + Menthol 1% Patch), on the Mid to upper back while being worn for 12 hours in healthy adult human subjects.

Start Date01 Jul 2021

Sponsor / Collaborator

Scilex Pharmaceuticals, Inc.

100 Clinical Results associated with Menthol/Methyl Salicylate

100 Translational Medicine associated with Menthol/Methyl Salicylate

100 Patents (Medical) associated with Menthol/Methyl Salicylate

Literatures (Medical) associated with Menthol/Methyl Salicylate

17 Jun 2022·Recent Patents on NanotechnologyQ4 · MATERIALS SCIENCE

WITHDRAWN: Development, In Vitro and Ex-Vivo Assessment of CAP Liposomal Film for Dermal Delivery

Q4 · MATERIALS SCIENCE

Article

Author: babu, Nikhilesh ; Nimmathota, Madhavi ; Beeravelli, Sudhakar ; Murthy Kolapalli, Venkata Ramana

The article has been withdrawn at the request of the editor of the journal Recent Patents on Nanotechnology due to incoherent content. Bentham Science apologizes to the readers of the journal for any inconvenience this may have caused. The Bentham Editorial Policy on Article Withdrawal can be found at https://benthamscience.com/editorial-policies-main.phpBentham Science Disclaimer: It is a condition of publication that manuscripts submitted to this journal have not been published and will not be simultaneously submitted or published elsewhere. Furthermore, any data, illustration, structure or table that has been published elsewhere must be reported, and copyright permission for reproduction must be obtained. Plagiarism is strictly forbidden, and by submitting the article for publication the authors agree that the publishers have the legal right to take appropriate action against the authors, if plagiarism or fabricated information is discovered. By submitting a manuscript, the authors agree that the copyright of their article is transferred to the publishers if and when the article is accepted for publication.

100 Deals associated with Menthol/Methyl Salicylate

External Link

KEGG	Wiki	ATC	Drug Bank
-	-	N02	-

R&D Status

10 top approved records.

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Indication	Country/Location	Organization	Date
Pain	US	Hisamitsu Pharmaceutical Co., Inc.	20 Feb 2008

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