Last update 16 May 2025

HRS-4800

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Nav1.8 inhibitor(Hengrui Medicine)
Target
Nav1.8
Action
blockers
Mechanism
Nav1.8 blockers(Sodium channel protein type X alpha subunit blockers)
Therapeutic Areas
Nervous System DiseasesOther Diseases
Active Indication
Pain, Postoperative
Inactive Indication
Peripheral neuralgia
Originator Organization
Jiangsu Hengrui Pharmaceuticals Co., Ltd.Jiangsu Hengrui Pharmaceuticals Co., Ltd.
Active Organization
Jiangsu Hengrui Pharmaceuticals Co., Ltd.Jiangsu Hengrui Pharmaceuticals Co., Ltd.
Inactive Organization
Luzsana Biotechnology, Inc.Luzsana Biotechnology, Inc.Atridia Pty Ltd.
License Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Related

6
Clinical Trials associated with HRS-4800
ChiCTR2200055811
/ RecruitingPhase 2IIT
A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel, Phase IIa Clinical Trial to Evaluate the Efficacy and Safety of HRS4800 Tablets for the Treatment of Postoperative Pain of Impacted Teeth
CTR20220048
/ CompletedPhase 2
HRS4800片用于阻生齿拔除术后镇痛的有效性和安全性的多中心、随机、双盲、安慰剂平行对照IIa期临床研究
[Translation] A multicenter, randomized, double-blind, placebo-controlled phase IIa clinical study on the efficacy and safety of HRS4800 tablets for postoperative analgesia after impacted tooth extraction
NCT05318846
/ CompletedPhase 2
A Multicenter, Randomized, Double-blind, Placebo-controlled, Phase IIa Clinical Trial to Evaluate the Efficacy and Safety of HRS4800 Tablets for Postoperative Analgesia After Impacted Teeth Removal Surgery
100 Clinical Results associated with HRS-4800
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100 Translational Medicine associated with HRS-4800
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100 Patents (Medical) associated with HRS-4800
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100 Deals associated with HRS-4800
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Pain, PostoperativePhase 2
China
Jiangsu Hengrui Pharmaceuticals Co., Ltd.Jiangsu Hengrui Pharmaceuticals Co., Ltd.
14 Jan 2022
PainPhase 1
Australia
Atridia Pty Ltd.
12 Nov 2020
Peripheral neuralgiaPreclinical
United States
Luzsana Biotechnology, Inc.Luzsana Biotechnology, Inc.
18 May 2022
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Clinical Result

Indication
Phase
Evaluation
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Core Patent

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Clinical Trial

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Approval

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Regulation

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