Last update 01 Nov 2024

NCGC-1481

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Target
FLT3 x IRAK1 x IRAK4
Mechanism
FLT3 inhibitors(Tyrosine-protein kinase receptor FLT3 inhibitors), IRAK1 antagonists(Interleukin-1 receptor-associated kinase 1 antagonists), IRAK4 inhibitors(Interleukin-1 receptor-associated kinase 4 inhibitors)
Therapeutic Areas
NeoplasmsHemic and Lymphatic Diseases
Active Indication
Acute Myeloid LeukemiaMyelodysplastic Syndromes
Inactive Indication-
Originator Organization
National Center for Advancing Translational SciencesNational Center for Advancing Translational Sciences
Active Organization
National Center for Advancing Translational SciencesNational Center for Advancing Translational Sciences
Inactive Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with NCGC-1481
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100 Translational Medicine associated with NCGC-1481
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100 Patents (Medical) associated with NCGC-1481
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1
Literatures (Medical) associated with NCGC-1481
09 Mar 2020Journal of Clinical InvestigationQ1 · MEDICINE
Targeting AML-associated FLT3 mutations with a type I kinase inhibitor
Q1 · MEDICINE
100 Deals associated with NCGC-1481
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute Myeloid LeukemiaPreclinical
US
National Center for Advancing Translational SciencesNational Center for Advancing Translational Sciences
-
Myelodysplastic SyndromesPreclinical
US
National Center for Advancing Translational SciencesNational Center for Advancing Translational Sciences
-
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Clinical Result

Indication
Phase
Evaluation
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Approval

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Regulation

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