Last update 16 Jul 2025

Jh-XIII-05-1

Overview

Basic Info

Drug Type
Proteolysis-targeting chimeras (PROTAC)
Synonyms
JH-XIII-05
Target
IRAK1 x IRAK4
Action
degraders
Mechanism
IRAK1 degraders(Interleukin-1 receptor-associated kinase 1 degraders), IRAK4 degraders(Interleukin-1 receptor-associated kinase 4 degraders)
Therapeutic Areas
NeoplasmsImmune System DiseasesHemic and Lymphatic Diseases
Active Indication
B-Cell LymphomaLymphoma
Inactive Indication-
Originator Organization
Dana-Farber Cancer Institute, Inc.Dana-Farber Cancer Institute, Inc.
Active Organization
Harvard Medical SchoolHarvard Medical SchoolDana-Farber Cancer Institute, Inc.Dana-Farber Cancer Institute, Inc.
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with Jh-XIII-05-1
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100 Translational Medicine associated with Jh-XIII-05-1
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100 Patents (Medical) associated with Jh-XIII-05-1
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100 Deals associated with Jh-XIII-05-1
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
B-Cell LymphomaPreclinical
United States
Harvard Medical SchoolHarvard Medical School
06 Dec 2024
LymphomaPreclinical
United States
Dana-Farber Cancer Institute, Inc.Dana-Farber Cancer Institute, Inc.
01 Jun 2024
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Clinical Result

Indication
Phase
Evaluation
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Deal

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Clinical Trial

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Approval

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Regulation

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