TUL12101

Primary objective: To evaluate the clinical efficacy of TUL12101 eye drops in the treatment of moderate to severe dry eye based on the changes in Schirmer I test results from baseline and the changes in dry eye symptom scores from baseline. Secondary objective: To evaluate the clinical efficacy and safety of TUL12101 eye drops in the treatment of moderate to severe dry eye. To evaluate the PK characteristics of TUL12101 eye drops in the blood of patients with moderate to severe dry eye. To evaluate the PK and PD characteristics of TUL12101 eye drops in the tears of patients with moderate to severe dry eye.