Last update 23 Jan 2025

CNV-2197944

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Target
Cav2.2
Mechanism
Cav2.2 blockers(Voltage-gated N-type calcium channel alpha-1B subunit blockers)
Therapeutic Areas
Nervous System DiseasesEndocrinology and Metabolic Disease
Active Indication
Diabetic NeuropathiesNeuralgia, Postherpetic
Inactive Indication
Diabetic peripheral neuropathy
Originator Organization
GSK PlcGSK Plc
Active Organization
Biogen, Inc.Biogen, Inc.GSK PlcGSK Plc
Inactive Organization
Convergence Pharmaceuticals, Inc.Calchan Ltd.Calchan Ltd.
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Related

4
Clinical Trials associated with CNV-2197944
EUCTR2013-000407-16-BG
/ Not yet recruitingNot Applicable
A randomised three week double-blind crossover study to compare the efficacy and safety of CNV2197944 75 mg tid versus placebo in the treatment of neuropathic pain in patients with diabetic peripheral neuropathy
NCT01893125
/ CompletedPhase 2
A Randomised Three Week Double-blind Crossover Study to Compare the Efficacy and Safety of CNV2197944 75 mg Tid Versus Placebo in the Treatment of Neuropathic Pain in Patients With Diabetic Peripheral Neuropathy
EUCTR2012-002903-16-BG
/ Not yet recruitingNot Applicable
A randomised, double-blind, crossover study to compare the efficacy and safety of CNV2197944 75 mg tid versus placebo in patients with post-herpetic neuralgia
100 Clinical Results associated with CNV-2197944
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100 Translational Medicine associated with CNV-2197944
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100 Patents (Medical) associated with CNV-2197944
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100 Deals associated with CNV-2197944
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External Link

KEGGWikiATCDrug Bank
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DB15229

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetic NeuropathiesPhase 2-
Biogen, Inc.Biogen, Inc.
-
Diabetic NeuropathiesPhase 2-
GSK PlcGSK Plc
-
Neuralgia, PostherpeticPhase 2-
GSK PlcGSK Plc
-
Neuralgia, PostherpeticPhase 2-
Biogen, Inc.Biogen, Inc.
-
Diabetic peripheral neuropathyPhase 1
HU
Convergence Pharmaceuticals, Inc.
01 Aug 2013
NeuralgiaPhase 1
HU
Convergence Pharmaceuticals, Inc.
01 Aug 2013
PainPhase 1
GB
Calchan Ltd.Calchan Ltd.
-
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Clinical Result

Indication
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Approval

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Regulation

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