Delving into the Latest Updates on Enriched hematopoetic stem cell infusion(University of Louisville) with Synapse

Overview

Basic Info

Drug Type

Stem cell therapy

Synonyms-

Target-

Mechanism-

Therapeutic Areas

Immune System DiseasesNervous System DiseasesCongenital Disorders+ [4]

Active Indication-

Inactive Indication

AdrenoleukodystrophyAlpha-MannosidosisAlpha-Thalassemia+ [14]

Originator Organization

University of Louisville

Active Organization-

Inactive Organization

University of Louisville

Talaris Therapeutics, Inc.

Drug Highest PhaseDiscontinuedPhase 2

First Approval Date-

Regulation-

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To study the effect of the stem cells therapy autologous mononuclear from the bone marrow, autologous progenitor endothelial CD133 cells from the bone marrow and autologous mesenchymal stem cells from adipose tissue on the inflammatory cytokines, the resistance to insulin and the decrease of the needs of insulin, besides evaluates the safety, viability and efficiency of the intra-arterial infusion of stem cells in diabetic patients type 2 with CLI.

Start Date01 Sep 2011

Sponsor / Collaborator-

NCT01419704 / WithdrawnPhase 1/2

Phase I/II Pilot Study of Mixed Chimerism to Treat Hemoglobinopathies

The goal of this research study is to establish chimerism and avoid graft-versus-host disease in patients with hemoglobinopathies.

Start Date01 May 2011

Sponsor / Collaborator

Talaris Therapeutics, Inc.

[+1]

NCT01372228 / TerminatedPhase 1/2

Phase I/II Pilot Study of Mixed Chimerism to Treat Inherited Metabolic Disorders

The goal of this research study is to establish chimerism and avoid graft-versus-host-disease (GVHD) in patients with inherited metabolic disorders.

Start Date01 Apr 2011

Sponsor / Collaborator

Talaris Therapeutics, Inc.

[+1]

100 Clinical Results associated with Enriched hematopoetic stem cell infusion(University of Louisville)

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100 Translational Medicine associated with Enriched hematopoetic stem cell infusion(University of Louisville)

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100 Patents (Medical) associated with Enriched hematopoetic stem cell infusion(University of Louisville)

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100 Deals associated with Enriched hematopoetic stem cell infusion(University of Louisville)

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R&D Status

10 top R&D records.

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Indication	Highest Phase	Country/Location	Organization	Date
Leukodystrophy, Globoid Cell	Phase 2	US	Talaris Therapeutics, Inc.	01 Apr 2011
Sandhoff Disease	Phase 2	US	Talaris Therapeutics, Inc.	01 Apr 2011
Anemia, Sickle Cell	Phase 2	US	Talaris Therapeutics, Inc.	01 Jan 2005
Cardiac transplant rejection	Phase 2	-	University of Louisville	-
Graft vs Host Disease	Phase 2	-	University of Louisville	-
Leukodystrophy, Metachromatic	Phase 2	-	University of Louisville	-
Leukodystrophy, Metachromatic	Phase 2	-	University of Louisville	-
Multiple Sclerosis	Phase 2	-	University of Louisville	-
Renal transplant rejection	Phase 2	-	University of Louisville	-
Renal transplant rejection	Phase 2	-	University of Louisville	-

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Clinical Result

Indication

Phase

Evaluation

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Study	Phase	Population	Analyzed Enrollment	Group	Results	Evaluation	Publication Date


ASH2023	Not Applicable	Multiple Myeloma	108	BCMA CAR T therapy	kfhbnmvotq(nnsotwcwcd) = ptgxtfsueb jnsrhixdkx (jetdklqeuo ) View more	-	11 Dec 2023
				Stem cell infusion	kfhbnmvotq(nnsotwcwcd) = ecrgfeppll jnsrhixdkx (jetdklqeuo ) View more