Last update 13 Nov 2024

FR-158999

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
FR158999
Target
Fibrinogen x GP IIb/IIIa
Mechanism
Fibrinogen inhibitors, GP IIb/IIIa antagonists(Integrin alpha-IIb/beta-3 antagonists), Platelet aggregation inhibitors
Therapeutic Areas
Cardiovascular Diseases
Active Indication-
Inactive Indication
Thrombosis
Originator Organization
Astellas Pharma, Inc.Astellas Pharma, Inc.
Active Organization-
Inactive Organization
Fujisawa Pharmaceutical Co., Ltd.Astellas Pharma, Inc.Astellas Pharma, Inc.
Drug Highest PhaseDiscontinuedPhase 1
First Approval Date-
Regulation-
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Structure

Molecular FormulaC24H35N5O8S
InChIKeyFPOQHPVEVPIFME-RXVVDRJESA-N
CAS Registry160138-41-0

Related

100 Clinical Results associated with FR-158999
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100 Translational Medicine associated with FR-158999
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100 Patents (Medical) associated with FR-158999
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1
Literatures (Medical) associated with FR-158999
01 Sep 1998Bioorganic & medicinal chemistry lettersQ4 · MEDICINE
QSAR study of the peptidic fibrinogen inhibitors FK633, FR158999 and related derivatives, using a novel and useful hydrophobic descriptor (logPmw)
Q4 · MEDICINE
100 Deals associated with FR-158999
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
ThrombosisPhase 1-
Astellas Pharma, Inc.Astellas Pharma, Inc.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Approval

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Regulation

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