Last update 21 Jun 2025

CART-PSMA-TGFβRDN cell therapy(Tceleron Therapeutics)

Overview

Basic Info

Drug Type
Autologous CAR-T
Synonyms-
Target
PSMA x TGF-β
Action
inhibitors
Mechanism
PSMA inhibitors(Prostate-specific membrane antigen inhibitors), TGF-β inhibitors(Transforming growth factor beta inhibitors), Gene transference(Gene transference)
Therapeutic Areas
NeoplasmsUrogenital Diseases
Active Indication-
Inactive Indication
Metastatic castration-resistant prostate cancer
Originator Organization
Tceleron Therapeutics, Inc.
Active Organization-
Inactive Organization
Tceleron Therapeutics, Inc.
License Organization-
Drug Highest PhaseDiscontinuedPhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with CART-PSMA-TGFβRDN cell therapy(Tceleron Therapeutics)
NCT04227275
/ TerminatedPhase 1
A Phase 1 Open-Label, Multi-Center Study of PSMA Targeted Genetically Modified Chimeric Antigen Receptor T Cells in Patients With Metastatic Castration Resistant Prostate Cancer
100 Clinical Results associated with CART-PSMA-TGFβRDN cell therapy(Tceleron Therapeutics)
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100 Translational Medicine associated with CART-PSMA-TGFβRDN cell therapy(Tceleron Therapeutics)
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100 Patents (Medical) associated with CART-PSMA-TGFβRDN cell therapy(Tceleron Therapeutics)
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100 Deals associated with CART-PSMA-TGFβRDN cell therapy(Tceleron Therapeutics)
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Metastatic castration-resistant prostate cancerPhase 1
United States
Tceleron Therapeutics, Inc.
22 Nov 2019
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Clinical Result

Indication
Phase
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Core Patent

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Clinical Trial

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Approval

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Regulation

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