Last update 26 Apr 2025

CYRS-1542

Overview

Basic Info

Drug Type
Degradable Molecular Glue
Synonyms
CYRS 1542, CYRS1542
Target
CRBN x GSPT1
Action
inhibitors, degraders
Mechanism
CRBN inhibitors(Cereblon inhibitors), GSPT1 degraders(G1 to S phase transition 1 degraders)
Therapeutic Areas
NeoplasmsHemic and Lymphatic Diseases
Active Indication
Neuroendocrine TumorsHematologic NeoplasmsSolid tumor
Inactive Indication-
Originator Organization
Cyrus Therapeutics, Inc.Cyrus Therapeutics, Inc.Startup
Active Organization
St. Jude Children's Research Hospital, Inc.St. Jude Children's Research Hospital, Inc.Cyrus Therapeutics, Inc.Cyrus Therapeutics, Inc.StartupSeoul National UniversitySeoul National University
Inactive Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with CYRS-1542
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100 Translational Medicine associated with CYRS-1542
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100 Patents (Medical) associated with CYRS-1542
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100 Deals associated with CYRS-1542
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Neuroendocrine TumorsPreclinical
South Korea
Seoul National UniversitySeoul National University
27 Apr 2025
Neuroendocrine TumorsPreclinical
South Korea
Cyrus Therapeutics, Inc.Cyrus Therapeutics, Inc.Startup
27 Apr 2025
Hematologic NeoplasmsPreclinical
South Korea
St. Jude Children's Research Hospital, Inc.St. Jude Children's Research Hospital, Inc.
04 Jan 2024
Hematologic NeoplasmsPreclinical
South Korea
Cyrus Therapeutics, Inc.Cyrus Therapeutics, Inc.Startup
04 Jan 2024
Solid tumorPreclinical
South Korea
St. Jude Children's Research Hospital, Inc.St. Jude Children's Research Hospital, Inc.
04 Jan 2024
Solid tumorPreclinical
South Korea
Cyrus Therapeutics, Inc.Cyrus Therapeutics, Inc.Startup
04 Jan 2024
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Clinical Result

Indication
Phase
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Approval

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Regulation

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