Last update 19 Jul 2025

YS-001

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
YS-001, YS001
Target
PI3Kα x mTORC1 x mTORC2
Action
inhibitors
Mechanism
PI3Kα inhibitors(Phosphatidylinositol 3 kinase alpha inhibitors), mTORC1 inhibitors(Mammalian target of Rapamycin (mTORC1) inhibitors), mTORC2 inhibitors(mTOR Complex 2 inhibitors)
Therapeutic Areas
NeoplasmsSkin and Musculoskeletal Diseases
Active Indication
Advanced Malignant Solid NeoplasmHormone receptor positive HER2 negative breast cancer
Inactive Indication-
Originator Organization
Jiangsu Wuzhong Medicine Group Co., Ltd.Jiangsu Wuzhong Medicine Group Co., Ltd.
Active Organization
Suzhou Zerun Biotechnology Co., Ltd.Suzhou Pharmaceutical FactorySuzhou Pharmaceutical Factory
Inactive Organization-
License Organization
Jiangsu Wuzhong Medicine Group Co., Ltd.Jiangsu Wuzhong Medicine Group Co., Ltd.Hangzhou Yusheng Pharmaceutical Technology Co., Ltd.
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with YS-001
CTR20212794
/ RecruitingPhase 1
YS001胶囊治疗晚期恶性实体瘤患者的开放标签、多中心、剂量递增和扩展I期临床试验
[Translation] An open-label, multicenter, dose-escalation and expansion phase I clinical trial of YS001 capsules in patients with advanced malignant solid tumors
100 Clinical Results associated with YS-001
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100 Translational Medicine associated with YS-001
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100 Patents (Medical) associated with YS-001
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100 Deals associated with YS-001
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 1
China
Suzhou Zerun Biotechnology Co., Ltd.
29 Dec 2021
Advanced Malignant Solid NeoplasmPhase 1
China
Suzhou Pharmaceutical FactorySuzhou Pharmaceutical Factory
29 Dec 2021
Hormone receptor positive HER2 negative breast cancerIND Approval
China
Suzhou Zerun Biotechnology Co., Ltd.
08 Jan 2024
Hormone receptor positive HER2 negative breast cancerIND Approval
China
Suzhou Pharmaceutical FactorySuzhou Pharmaceutical Factory
08 Jan 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Clinical Trial

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Approval

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Regulation

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