Last update 28 Feb 2026

RQ-00434739

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
RQ 00434739, RQ00434739, XG-2002
+ [1]
Target
TRPM8
Action
antagonists
Mechanism
TRPM8 antagonists(Transient receptor potential cation channel subfamily M member 8 antagonists)
Therapeutic Areas
Nervous System DiseasesOther Diseases
Active Indication
Chronic PainOstealgia
Inactive Indication
HeadacheInflammationNeuralgia
Originator Organization
RaQualia Pharma, Inc.RaQualia Pharma, Inc.
Active Organization
RaQualia Pharma, Inc.RaQualia Pharma, Inc.Xgene Pharmaceutical, Inc.Xgene Pharmaceutical, Inc.
Inactive Organization-
License Organization
RaQualia Pharma, Inc.RaQualia Pharma, Inc.Xgene Pharmaceutical, Inc.Xgene Pharmaceutical, Inc.
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with RQ-00434739
ACTRN12624000245594
/ RecruitingPhase 1
A Phase I, Randomized, Double-blind, Placebo-controlled, Single-Ascending-Dose (SAD) Study to Evaluate the Safety, Tolerability, and Pharmacokinetics (PK) of XG2002 Oral Administration in Healthy Adult Volunteers
100 Clinical Results associated with RQ-00434739
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100 Translational Medicine associated with RQ-00434739
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100 Patents (Medical) associated with RQ-00434739
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100 Deals associated with RQ-00434739
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Chronic PainPhase 1
Australia
Xgene Pharmaceutical, Inc.Xgene Pharmaceutical, Inc.
20 Dec 2023
OstealgiaPhase 1-
Xgene Pharmaceutical, Inc.Xgene Pharmaceutical, Inc.
-
HeadachePreclinical
China
Xgene Pharmaceutical, Inc.Xgene Pharmaceutical, Inc.
12 Oct 2022
NeuralgiaPreclinical
Japan
RaQualia Pharma, Inc.RaQualia Pharma, Inc.
28 Aug 2016
InflammationPreclinical
Japan
RaQualia Pharma, Inc.RaQualia Pharma, Inc.
-
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Clinical Result

Indication
Phase
Evaluation
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Phase
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Clinical Trial

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Approval

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Regulation

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