Last update 13 Sep 2025

HP-515

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
HP515
Target
THR-β
Action
inhibitors
Mechanism
THR-β inhibitors(Thyroid hormone receptor beta inhibitors)
Therapeutic Areas
Digestive System DisordersEndocrinology and Metabolic Disease
Active Indication
Metabolic dysfunction-associated steatotic liver diseaseNonalcoholic SteatohepatitisDiabetes Mellitus+ [1]
Inactive Indication-
Originator Organization
Hinova Pharmaceuticals, Inc.Hinova Pharmaceuticals, Inc.
Active Organization
Hinova Pharmaceuticals, Inc.Hinova Pharmaceuticals, Inc.Hinova Pharmaceuticals (Usa) Inc
Inactive Organization-
License Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with HP-515
CTR20253542
/ Not yet recruitingPhase 2
评估HP515片在非酒精性脂肪性肝病参与者中的有效性、安全性、药代动力学、药效学的Ⅱa期临床试验
[Translation] A Phase IIa clinical trial evaluating the efficacy, safety, pharmacokinetics, and pharmacodynamics of HP515 tablets in participants with non-alcoholic fatty liver disease
CTR20244934
/ Not yet recruitingPhase 1
评估HP515片在健康受试者中单次和多次剂量递增给药的安全性、耐受性、药代动力学、药效动力学及食物影响的 I期临床试验
[Translation] Phase I clinical trial to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics and food effects of single and multiple ascending doses of HP515 tablets in healthy subjects
100 Clinical Results associated with HP-515
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100 Translational Medicine associated with HP-515
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100 Patents (Medical) associated with HP-515
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100 Deals associated with HP-515
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Metabolic dysfunction-associated steatotic liver diseasePhase 2
China
Hinova Pharmaceuticals, Inc.Hinova Pharmaceuticals, Inc.
10 Sep 2025
Nonalcoholic SteatohepatitisPhase 1
China
Hinova Pharmaceuticals, Inc.Hinova Pharmaceuticals, Inc.
27 Dec 2024
Diabetes MellitusPreclinical
China
Hinova Pharmaceuticals, Inc.Hinova Pharmaceuticals, Inc.
01 Jun 2025
ObesityPreclinical
China
Hinova Pharmaceuticals, Inc.Hinova Pharmaceuticals, Inc.
01 Jun 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Clinical Trial

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Approval

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Regulation

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