Recombinant botulinum toxin type A (Beijing Botvik)

The main purpose of Phase I is to evaluate the safety and tolerability of recombinant botulinum toxin type A BT001 for injection in subjects with moderate to severe glabellar lines; the secondary objectives of Phase I are: 1. Evaluate the immunogenicity of recombinant botulinum toxin type A BT001 for injection in subjects with moderate to severe glabellar lines; 2. Evaluate the effectiveness of recombinant botulinum toxin type A BT001 for injection in subjects with moderate to severe glabellar lines. The main purpose of Phase II is to evaluate the effectiveness of recombinant botulinum toxin type A BT001 for injection in subjects with moderate to severe glabellar lines; the secondary objectives of Phase II are: 1. Evaluate other effectiveness of recombinant botulinum toxin type A BT001 for injection in subjects with moderate to severe glabellar lines; 2. Evaluate the safety of recombinant botulinum toxin type A BT001 for injection in subjects with moderate to severe glabellar lines; 3. Evaluate the immunogenicity of recombinant botulinum toxin type A BT001 for injection in subjects with moderate to severe glabellar lines.