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Last update 16 May 2025
Dextromethorphan Hydrobromide/Promethazine Hydrochloride
Last update 16 May 2025
Overview
Basic Info
Drug Type Small molecule drug |
Synonyms PROMETHAZINE HYDROCHLORIDE/DEXTROMETHORPHAN HYDROBROMIDE |
Action antagonists |
Mechanism H1 receptor antagonists(Histamine H1 receptor antagonists), NMDA receptor antagonists(Glutamate [NMDA] receptor antagonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhaseApproved |
First Approval Date United States (03 Dec 1957), |
Regulation- |
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Structure/Sequence
Molecular FormulaC18H28BrNO2 |
InChIKeySTTADZBLEUMJRG-IKNOHUQMSA-N |
CAS Registry6700-34-1 |
View All Structures (2)
R&D Status
10 top approved records. to view more data
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| Indication | Country/Location | Organization | Date |
|---|---|---|---|
| Anaphylaxis | United States | 03 Dec 1957 | |
| Angioedema | United States | 03 Dec 1957 | |
| Anxiety Disorders | United States | 03 Dec 1957 | |
| Conjunctivitis, Allergic | United States | 03 Dec 1957 | |
| Familial Dermographism | United States | 03 Dec 1957 | |
| Motion Sickness | United States | 03 Dec 1957 | |
| Pain, Postoperative | United States | 03 Dec 1957 | |
| Postoperative Nausea and Vomiting | United States | 03 Dec 1957 | |
| Rhinitis, Allergic | United States | 03 Dec 1957 | |
| Rhinitis, Vasomotor | United States | 03 Dec 1957 | |
| Sedation | United States | 03 Dec 1957 | |
| Sleep Initiation and Maintenance Disorders | United States | 03 Dec 1957 | |
| Urticaria | United States | 03 Dec 1957 | |
| Vomiting | United States | 03 Dec 1957 |
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Clinical Result
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