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Overview

Basic Info

Drug Type

Small molecule drug

Synonyms

ASIM, Sulfasim

Target-

Mechanism

Immunomodulators

Therapeutic Areas

Immune System DiseasesOther Diseases

Active Indication-

Inactive Indication

Drug HypersensitivityHypersensitivity

Originator Organization

Cortech, Inc.

Active Organization-

Inactive Organization

Cortech, Inc.

Drug Highest PhaseDiscontinuedPhase 1

First Approval Date-

Regulation-

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This paper presents an approach that combines the generalized multimode nonlinear Schrodinger equation with a transmission model to analyze spatiotemporal characteristics of multimode interference in single mode/large mode area fiber–graded-index multimode fiber–single mode fiber (SMF/LMA-GIMF-SMF) structures for the first time. Approximated self-imaging (ASIM) behavior in GIMF and the study of the latter structure used in spatiotemporal mode-locked fiber lasers are first demonstrated. Simulations show that these structures can work as saturable absorbers enabling high-energy pulse output due to nonlinear intermodal interactions and intensity-dependent multimode interference. Otherwise, underlying ASIM is proven that it can perturb the transmission of SMF/LMA-GIMF-SMF, causing instability of their saturable-absorption characteristics. This paper provides a theoretical guide for many applications, such as beam shaping, mode conversion, and high-energy ultrafast fiber laser.

01 Jan 1990·The Internist

A decade to remember: ASIM and RBRVS.

Article

Author: Doherty, R B

100 Deals associated with CI-0694

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