Last update 21 Nov 2024

Alclometasone Dipropionate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Alclometasone, Alclometasone dipropionate (JAN/USP)
+ [11]
Target
Mechanism
GR agonists(Glucocorticoid receptor agonists)
Active Indication
Inactive Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (14 Dec 1982),
Regulation-
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Structure

Molecular FormulaC28H37ClO7
InChIKeyDJHCCTTVDRAMEH-DUUJBDRPSA-N
CAS Registry66734-13-2

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Dermatitis
GB
26 Apr 1995
Pruritus
GB
26 Apr 1995
Eczema
JP
29 Mar 1988
Erythema
JP
29 Mar 1988
Insect Bites and Stings
JP
29 Mar 1988
Keratoderma, Palmoplantar
JP
29 Mar 1988
Lichen Planus
JP
29 Mar 1988
Lupus Erythematosus, Discoid
JP
29 Mar 1988
Prurigo
JP
29 Mar 1988
Psoriasis
JP
29 Mar 1988
Purpura
JP
29 Mar 1988
Roseolovirus Infections
JP
29 Mar 1988
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
236
(Cohort I: Arm A (Dacomitinib 45 mg + Doxycycline Placebo))
opuzldtrkw(xviypltjxg) = hnhkothcuf ghthremcmy (tbnusujctd, nsuzdtnieh - qoevmioens)
-
17 Aug 2016
(Cohort I: Arm B (Dacomitinib 45 mg + Doxycycline 100 mg))
opuzldtrkw(xviypltjxg) = ynhcoivvnk ghthremcmy (tbnusujctd, xslormitzo - kdgjxoxszp)
Phase 2
112
aomdzldaxx(wzcbocuaez) = improved with prophylactic doxy, but not alclo; prophylactic probiotic was not associated with improved CTCAE or PRO otmlykvrnd (efiivbkhvo )
-
08 Sep 2015
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Regulation

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