[Translation] A multicenter, single-dose, dose-escalation clinical trial to explore the safety and tolerability of human umbilical cord mesenchymal stem cell injection in the treatment of knee osteoarthritis
主要目的
探索人脐带间充质干细胞注射液治疗膝骨关节炎的安全性和耐受性。 次要目的
为后续临床试验推荐合适的细胞治疗剂量。
探索人脐带间充质干细胞注射液治疗膝骨关节炎的初步有效性。
探索人脐带间充质干细胞注射液治疗膝骨关节炎的免疫原性。
[Translation] Primary objective
To explore the safety and tolerability of human umbilical cord mesenchymal stem cell injection in the treatment of knee osteoarthritis. Secondary objective
To recommend appropriate cell therapy doses for subsequent clinical trials.
To explore the preliminary effectiveness of human umbilical cord mesenchymal stem cell injection in the treatment of knee osteoarthritis.
To explore the immunogenicity of human umbilical cord mesenchymal stem cell injection in the treatment of knee osteoarthritis.