Last update 13 Sep 2025

CN120136841

Patent Mining

Overview

Basic Info

Drug Type
Proteolysis-targeting chimeras (PROTAC)
Synonyms-
Target
CRBN x MDM2 x SUPT5H x Ubiquitin ligase x VHL
Action
inhibitors
Mechanism
CRBN inhibitors(Cereblon inhibitors), MDM2 inhibitors(p53-binding protein Mdm-2 inhibitors), Ubiquitin ligase inhibitors(E3 ubiquitin ligase components inhibitors)
Therapeutic Areas
NeoplasmsImmune System DiseasesOther Diseases
Active Indication
Immune System DiseasesInflammationNeoplasms
Inactive Indication-
Originator Organization
Suzhou Institute of Systems MedicineSuzhou Institute of Systems Medicine
Active Organization
Suzhou Institute of Systems MedicineSuzhou Institute of Systems Medicine
Inactive Organization-
License Organization-
Drug Highest PhaseDiscovery
First Approval Date-
Regulation-

Related

100 Clinical Results associated with CN120136841
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100 Translational Medicine associated with CN120136841
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100 Patents (Medical) associated with CN120136841
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100 Deals associated with CN120136841
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Immune System DiseasesDiscovery-
Suzhou Institute of Systems MedicineSuzhou Institute of Systems Medicine
13 Jun 2025
InflammationDiscovery-
Suzhou Institute of Systems MedicineSuzhou Institute of Systems Medicine
13 Jun 2025
NeoplasmsDiscovery-
Suzhou Institute of Systems MedicineSuzhou Institute of Systems Medicine
13 Jun 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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