Last update 14 Dec 2024

B7H3 IL-7Ra CAR T Cell (University of Chulalongkorn)

Overview

Basic Info

Drug Type
Autologous CAR-T
Synonyms
B7H3 specific CAR T cell with IL-7Ra signaling domain, B7H3 With IL-7 Receptor Alpha Signaling Chimeric Antigen Receptor T Cell, CDM03 CAR T Cell(University of Chulalongkorn)
Target
CD276
Mechanism
CD276 modulators(CD276 antigen modulators)
Therapeutic Areas
NeoplasmsNervous System DiseasesOther Diseases
Active Indication
Relapsed Solid NeoplasmDiffuse Intrinsic Pontine Glioma
Inactive Indication-
Originator Organization
University of Chulalongkorn
Active Organization
University of Chulalongkorn
Inactive Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with B7H3 IL-7Ra CAR T Cell (University of Chulalongkorn)
NCT06612645 / Not yet recruitingPhase 1IIT
Safety and Efficacy of B7H3 With IL-7 Receptor Alpha Signaling Chimeric Antigen Receptor T Cell (CMD03) in Relapse and Refractory Pediatric Solid Tumors
NCT06221553 / RecruitingPhase 1IIT
Safety and Efficacy of Intraventricular Infusion of B7H3 With IL-7 Receptor Alpha Signaling Chimeric Antigen Receptor T Cell in Diffuse Intrinsic Pontine Glioma
100 Clinical Results associated with B7H3 IL-7Ra CAR T Cell (University of Chulalongkorn)
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100 Translational Medicine associated with B7H3 IL-7Ra CAR T Cell (University of Chulalongkorn)
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100 Patents (Medical) associated with B7H3 IL-7Ra CAR T Cell (University of Chulalongkorn)
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100 Deals associated with B7H3 IL-7Ra CAR T Cell (University of Chulalongkorn)
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Relapsed Solid NeoplasmPhase 1
TH
University of Chulalongkorn
01 Dec 2024
Diffuse Intrinsic Pontine GliomaPhase 1
TH
University of Chulalongkorn
01 Mar 2024
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Clinical Result

Indication
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Regulation

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