Last update 01 Nov 2024

Buspirone Hydrochloride/Melatonin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Buspirone/melatonin
Target
5-HT1A receptor x D2 receptor x Melatonin receptor
Mechanism
5-HT1A receptor partial agonists(Serotonin 1a (5-HT1a) receptor partial agonists), D2 receptor antagonists(Dopamine D2 receptor antagonists), Melatonin receptor agonists
Therapeutic Areas
Other Diseases
Active Indication-
Inactive Indication
Depressive Disorder, Major
Originator Organization
BrainCells, Inc.BrainCells, Inc.
Active Organization-
Inactive Organization
BrainCells, Inc.BrainCells, Inc.
Drug Highest PhaseDiscontinuedPhase 2
First Approval Date-
Regulation-
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Structure

Molecular FormulaC13H16N2O2
InChIKeyDRLFMBDRBRZALE-UHFFFAOYSA-N
CAS Registry73-31-4
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Related

2
Clinical Trials associated with Buspirone Hydrochloride/Melatonin
NL-OMON36120 / CompletedNot Applicable
A PHASE I, OPEN-LABEL, FIXED-SEQUENCE, THREE-PERIOD CROSSOVER TRIAL TO EVALUATE THE PHARMACOKINETICS OF TWO DIFFERENT TABLET FORMULATIONS OF BCI 952 COMPARED TO THE OVER-ENCAPSULATED BCI-952 PRODUCT COMPONENTS IN HEALTHY MALE SUBJECTS - BCI-952 three-period crossover bioequivalence study
NCT00731653 / CompletedPhase 2IIT
An Open-Label Extension Study to Assess the Tolerability of BCI-024 in Combination With BCI-049 in Patients With Major Depressive Disorder
100 Clinical Results associated with Buspirone Hydrochloride/Melatonin
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100 Translational Medicine associated with Buspirone Hydrochloride/Melatonin
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100 Patents (Medical) associated with Buspirone Hydrochloride/Melatonin
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100 Deals associated with Buspirone Hydrochloride/Melatonin
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Depressive Disorder, MajorPhase 2
US
BrainCells, Inc.BrainCells, Inc.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Clinical Trial

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Approval

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Regulation

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