Last update 28 May 2025

CD79b-19 CAR T Cells(Massachusetts General Hospital)

Overview

Basic Info

Drug Type
Autologous CAR-T
Synonyms-
Target
CD19 x CD79B
Action
modulators
Mechanism
CD19 modulators(B-lymphocyte antigen CD19 modulators), CD79B modulators(B-cell antigen receptor complex-associated protein beta chain modulators), Immunologic cytotoxicity
Therapeutic Areas
NeoplasmsImmune System DiseasesHemic and Lymphatic Diseases+ [1]
Active Indication
Follicular LymphomaHigh grade B-cell lymphomaMantle-Cell Lymphoma+ [4]
Inactive Indication-
Originator Organization
The Schwartz Center for Compassionate HealthcareThe Schwartz Center for Compassionate Healthcare
Active Organization
The Massachusetts General HospitalThe Massachusetts General Hospital
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with CD79b-19 CAR T Cells(Massachusetts General Hospital)
NCT06026319
/ RecruitingPhase 1IIT
A Phase I Study of Bivalent CD79b and CD19 Directed CAR T Cells in Patients With Relapsed/Refractory Non-Hodgkin Lymphoma
100 Clinical Results associated with CD79b-19 CAR T Cells(Massachusetts General Hospital)
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100 Translational Medicine associated with CD79b-19 CAR T Cells(Massachusetts General Hospital)
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100 Patents (Medical) associated with CD79b-19 CAR T Cells(Massachusetts General Hospital)
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100 Deals associated with CD79b-19 CAR T Cells(Massachusetts General Hospital)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Follicular LymphomaPhase 1
United States
The Massachusetts General HospitalThe Massachusetts General Hospital
26 Oct 2023
High grade B-cell lymphomaPhase 1
United States
The Massachusetts General HospitalThe Massachusetts General Hospital
26 Oct 2023
Mantle-Cell LymphomaPhase 1
United States
The Massachusetts General HospitalThe Massachusetts General Hospital
26 Oct 2023
Marginal Zone B-Cell LymphomaPhase 1
United States
The Massachusetts General HospitalThe Massachusetts General Hospital
26 Oct 2023
Mediastinal large B-cell lymphomaPhase 1
United States
The Massachusetts General HospitalThe Massachusetts General Hospital
26 Oct 2023
Non-Hodgkin's lymphoma refractoryPhase 1
United States
The Massachusetts General HospitalThe Massachusetts General Hospital
26 Oct 2023
Recurrent Non-Hodgkin LymphomaPhase 1
United States
The Massachusetts General HospitalThe Massachusetts General Hospital
26 Oct 2023
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Clinical Result

Indication
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Clinical Trial

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Approval

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Regulation

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