Last update 30 Sep 2025

VGN-R08

Overview

Basic Info

Drug Type
AAV based gene therapy
Synonyms
VGN-R08b, VGNR08
Target
GBA1
Action
stimulants
Mechanism
GBA stimulants(Beta-glucocerebrosidase stimulants), Gene transference(Gene transference)
Therapeutic Areas
Nervous System DiseasesCongenital DisordersEndocrinology and Metabolic Disease+ [1]
Active Indication
Gaucher Disease, Type 2Parkinson Disease
Inactive Indication-
Originator Organization
Shanghai Vitalgen Biopharma Co., Ltd.Shanghai Vitalgen Biopharma Co., Ltd.
Active Organization
Shanghai Vitalgen Biopharma Co., Ltd.Shanghai Vitalgen Biopharma Co., Ltd.
Tianze Yuntai (Shenzhen) Biomedical Co., Ltd.
Inactive Organization-
License Organization-
Drug Highest PhaseEarly Phase 1
First Approval Date-
RegulationRare Pediatric Disease (United States)
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Related

1
Clinical Trials associated with VGN-R08
NCT06272149
/ RecruitingEarly Phase 1IIT
An Exploratory Clinical Trial to Evaluate the Tolerability and Safety of VGN-R08b Via Intracerebroventricular Injection in Patients With Type II Gaucher Disease
100 Clinical Results associated with VGN-R08
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100 Translational Medicine associated with VGN-R08
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100 Patents (Medical) associated with VGN-R08
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100 Deals associated with VGN-R08
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Gaucher Disease, Type 2Phase 1
China
Shanghai Vitalgen Biopharma Co., Ltd.Shanghai Vitalgen Biopharma Co., Ltd.
01 Mar 2023
Parkinson DiseaseIND Approval
United States
Tianze Yuntai (Shenzhen) Biomedical Co., Ltd.
28 Sep 2025
Parkinson DiseaseIND Approval
China
Shanghai Vitalgen Biopharma Co., Ltd.Shanghai Vitalgen Biopharma Co., Ltd.
28 Sep 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Clinical Trial

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Approval

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Regulation

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