Last update 07 Jun 2025

CPD-145

Overview

Basic Info

Drug Type
Proteolysis-targeting chimeras (PROTAC)
Synonyms
CPD-145
Target
TrkA x TrkB x TrkC
Action
antagonists, inhibitors
Mechanism
TrkA antagonists(Nerve growth factor receptor Trk-A antagonists), TrkB inhibitors(Neurotrophic tyrosine kinase receptor type 2 inhibitors), TrkC inhibitors(Neurotrophic tyrosine kinase receptor type 3 inhibitors)
Therapeutic Areas
Neoplasms
Active Indication-
Inactive Indication
Neoplasms
Originator Organization
Usona InstituteUsona Institute
Active Organization-
Inactive Organization
Usona InstituteUsona Institute
License Organization-
Drug Highest PhasePendingPreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC42H42FN11O5
InChIKeyVTETXVUOPFSTLY-KWRHIPAJSA-N
CAS Registry2412056-79-0

Related

100 Clinical Results associated with CPD-145
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100 Translational Medicine associated with CPD-145
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100 Patents (Medical) associated with CPD-145
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100 Deals associated with CPD-145
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
NeoplasmsPreclinical
United States
Usona InstituteUsona Institute
18 May 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Clinical Trial

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Approval

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Regulation

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