Last update 13 Dec 2025

PM-1015

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
PM 1015, PM-1015
Target
CD73
Action
inhibitors
Mechanism
CD73 inhibitors(5-nucleotidase inhibitors)
Therapeutic Areas
NeoplasmsDigestive System Disorders
Active Indication-
Inactive Indication
Advanced Malignant Solid NeoplasmLiver CancerSolid tumor
Originator Organization
Biotheus, Inc.Biotheus, Inc.
Active Organization-
Inactive Organization
Biotheus, Inc.Biotheus, Inc.
License Organization
Biotheus, Inc.Biotheus, Inc.
Shanghai Genbase Biotechnology Co., Ltd.Shanghai Genbase Biotechnology Co., Ltd.
Drug Highest PhasePendingPhase 1
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with PM-1015
ChiCTR2200060403
/ Not yet recruitingPhase 1IIT
A phase I study to evaluate the tolerance, safety, pharmacokinetic characteristics and preliminary efficacy of PM1015 in patients with advanced solid tumors
NCT05950815
/ Unknown statusPhase 1
A Phase I Study to Evaluate the Tolerance, Safety, Pharmacokinetic Characteristics and Preliminary Efficacy of PM1015 in Patients With Advanced Solid Tumors
100 Clinical Results associated with PM-1015
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100 Translational Medicine associated with PM-1015
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100 Patents (Medical) associated with PM-1015
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100 Deals associated with PM-1015
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 1
China
Biotheus, Inc.Biotheus, Inc.
10 May 2022
Liver CancerPhase 1
China
Biotheus, Inc.Biotheus, Inc.
10 May 2022
Solid tumorPhase 1
China
Biotheus, Inc.Biotheus, Inc.
10 May 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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