Last update 26 Oct 2025

CTx-0294886

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
AMP-886, CTX-294886
Target
FAK x FLT3 x VEGFR3
Action
inhibitors, antagonists
Mechanism
FAK inhibitors(Focal adhesion kinase inhibitors), FLT3 inhibitors(Tyrosine-protein kinase receptor FLT3 inhibitors), VEGFR3 antagonists(Vascular endothelial growth factor receptor 3 antagonists)
Therapeutic Areas
NeoplasmsHemic and Lymphatic Diseases
Active Indication
Hematologic NeoplasmsSolid tumor
Inactive Indication
Pulmonary Fibrosis
Originator Organization
Cancer Therapeutics, Inc.Cancer Therapeutics, Inc.
Active Organization
Amplia Therapeutics Ltd.Amplia Therapeutics Ltd.
Inactive Organization
Cancer Therapeutics, Inc.Cancer Therapeutics, Inc.
Cancer Research Technology Ltd.Cancer Research Technology Ltd.
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with CTx-0294886
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100 Translational Medicine associated with CTx-0294886
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100 Patents (Medical) associated with CTx-0294886
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100 Deals associated with CTx-0294886
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hematologic NeoplasmsPreclinical-
Amplia Therapeutics Ltd.Amplia Therapeutics Ltd.
07 Feb 2024
Solid tumorPreclinical-
Amplia Therapeutics Ltd.Amplia Therapeutics Ltd.
07 Feb 2024
Pulmonary FibrosisPreclinical-
Cancer Therapeutics, Inc.Cancer Therapeutics, Inc.
-
Pulmonary FibrosisPreclinical-
Cancer Research Technology Ltd.Cancer Research Technology Ltd.
-
Pulmonary FibrosisPreclinical-
Amplia Therapeutics Ltd.Amplia Therapeutics Ltd.
-
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Clinical Result

Indication
Phase
Evaluation
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Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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