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Clinical Trials associated with Henagliflozein Proline/Retagliptin Phosphate/Metformin Hydrochloride [Translation] Food Effect Study of HR20031 Tablets in Healthy Volunteers
主要研究目的 :评价高脂饮食对健康志愿者单次口服HR20031后恒格列净、瑞格列汀和二甲双胍的药代动力学影响;
次要研究目的 :评价空腹与高脂餐后状态下健康受试者单次口服HR20031片的安全性和耐受性;评价高脂饮食对健康志愿者单次口服HR20031后瑞格列汀主要代谢产物瑞格列汀酸的药代动力学影响。
[Translation] Main study objectives: To evaluate the effect of a high-fat diet on the pharmacokinetics of hengagliflozin, repagliptin and metformin in healthy volunteers after a single oral administration of HR20031;
Secondary study objectives: To evaluate the safety and tolerability of a single oral administration of HR20031 tablets in healthy subjects in the fasting and high-fat meal state; To evaluate the effect of a high-fat diet on the pharmacokinetics of repagliptin acid, the main metabolite of repagliptin, in healthy volunteers after a single oral administration of HR20031.
A Bioequivalence Study of HR20031 Tablet in Healthy Subjects
The purpose of this study is to assess the bioequivalence between HR20031 FDC tablet and co-administration of SHR3824 tablets, SP2086 tablets and metformin XR tablets.
[Translation] Bioequivalence study of HR20031 tablets in healthy subjects
主要研究目的:评价健康受试者高脂餐后状态下单次口服受试制剂 HR20031 片和参比制剂脯氨酸恒格列净片、磷酸瑞格列汀、盐酸二甲双胍缓释片的生物等效性;
次要研究目的:评价健康受试者高脂餐后状态下单次口服受试制剂 HR20031 片和参比制剂脯氨酸恒格列净片、磷酸瑞格列汀、盐酸二甲双胍缓释片的安全性。
[Translation] The main purpose of the study is to evaluate the bioequivalence of the test preparation HR20031 tablets and the reference preparations of proline henggliflozin tablets, retagliptin phosphate, and metformin hydrochloride sustained-release tablets after a single oral administration in healthy subjects in the post-high-fat meal state;
The secondary purpose of the study is to evaluate the safety of the test preparation HR20031 tablets and the reference preparations of proline henggliflozin tablets, retagliptin phosphate, and metformin hydrochloride sustained-release tablets after a single oral administration in healthy subjects in the post-high-fat meal state.
100 Clinical Results associated with Henagliflozein Proline/Retagliptin Phosphate/Metformin Hydrochloride
100 Translational Medicine associated with Henagliflozein Proline/Retagliptin Phosphate/Metformin Hydrochloride
100 Patents (Medical) associated with Henagliflozein Proline/Retagliptin Phosphate/Metformin Hydrochloride
100 Deals associated with Henagliflozein Proline/Retagliptin Phosphate/Metformin Hydrochloride