Drug Type Small molecule drug |
Synonyms Henagliflozein Proline/Retagliptin Phosphate/Metformin Hydrochloride, 脯氨酸恒格列净/磷酸瑞格列汀/盐酸二甲双胍, HR 20031 + [3] |
Target |
Action inhibitors, activators |
Mechanism DPP-4 inhibitors(Dipeptidyl peptidase IV inhibitors), PRKAB1 activators(Protein kinase AMP-activated non-catalytic subunit beta 1 activators), SGLT2 inhibitors(Sodium/glucose cotransporter 2 inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization- |
Drug Highest PhaseApproved |
First Approval Date China (21 Oct 2025), |
Regulation- |
Molecular FormulaC22H24ClFO7 |
InChIKeyHYTPDMFFHVZBOR-VNXMGFANSA-N |
CAS Registry1623804-44-3 |
| Indication | Country/Location | Organization | Date |
|---|---|---|---|
| Diabetes Mellitus, Type 2 | China | 21 Oct 2025 |
Phase 1 | - | - | blqhxnldec(meijakfrmz) = 具有生物等效性 uvuwodldpo (rupqshfymd ) View more | Positive | 27 Oct 2025 | ||
Phase 1 | - | - | dmyppkxpik(wqzayruzkd) = 空腹与餐后状态下食物对恒格列净、瑞格列汀、二甲双胍的药代动力学影响不具有临床意义 gstspijfch (aljjzjuirq ) View more | Positive | 27 Oct 2025 | ||
Phase 3 | - | (三联高剂量组) | qxjmiyhnyo(vfhzzgzjmq) = mverwjhscw eigwizvikg (wbkcppkvqy ) View more | Positive | 27 Oct 2025 | ||
(三联低剂量组) | qxjmiyhnyo(vfhzzgzjmq) = euzeopahkj eigwizvikg (wbkcppkvqy ) View more |





