Last update 31 Dec 2025

ZX-8177

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
ZX 8177, ZX8177
Target
ENPP1
Action
inhibitors
Mechanism
ENPP1 inhibitors(Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 inhibitors)
Therapeutic Areas
Neoplasms
Active Indication
Advanced Malignant Solid Neoplasm
Inactive Indication-
Originator Organization
Nanjing Zenshine Pharmaceuticals Co., Ltd.Nanjing Zenshine Pharmaceuticals Co., Ltd.
Active Organization
Nanjing Zenshine Pharmaceuticals Co., Ltd.Nanjing Zenshine Pharmaceuticals Co., Ltd.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with ZX-8177
NCT07310134
/ Not yet recruitingPhase 1
An Open-Label, Multicenter Phase I Clinical Study on the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of Dose Escalation and Dose Expansion of ZX-8177 Tablets in Chinese Patients With Advanced Solid Tumors
100 Clinical Results associated with ZX-8177
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100 Translational Medicine associated with ZX-8177
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100 Patents (Medical) associated with ZX-8177
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100 Deals associated with ZX-8177
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 1
China
Nanjing Zenshine Pharmaceuticals Co., Ltd.Nanjing Zenshine Pharmaceuticals Co., Ltd.
19 Dec 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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