Last update 25 Oct 2025

KAR-2581

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
K-2000 series, KAR-2581, OS-HDI-3
Target
HDACs
Action
inhibitors
Mechanism
HDAC inhibitors(Histone deacetylase inhibitors), Epigenetic drug
Therapeutic Areas
NeoplasmsImmune System DiseasesNervous System Diseases+ [2]
Active Indication-
Inactive Indication
Graft RejectionMultiple SclerosisNeoplasms+ [3]
Originator Organization
Karus Therapeutics Ltd.Karus Therapeutics Ltd.
Active Organization-
Inactive Organization
Karus Therapeutics Ltd.Karus Therapeutics Ltd.
License Organization-
Drug Highest PhasePendingDiscovery
First Approval Date-
Regulation-

Related

100 Clinical Results associated with KAR-2581
Login to view more data
100 Translational Medicine associated with KAR-2581
Login to view more data
100 Patents (Medical) associated with KAR-2581
Login to view more data
100 Deals associated with KAR-2581
Login to view more data

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Graft RejectionDiscovery
United Kingdom
Karus Therapeutics Ltd.Karus Therapeutics Ltd.
-
Multiple SclerosisDiscovery
United Kingdom
Karus Therapeutics Ltd.Karus Therapeutics Ltd.
-
NeoplasmsDiscovery
United Kingdom
Karus Therapeutics Ltd.Karus Therapeutics Ltd.
-
PsoriasisDiscovery
United Kingdom
Karus Therapeutics Ltd.Karus Therapeutics Ltd.
-
Rheumatoid ArthritisDiscovery
United Kingdom
Karus Therapeutics Ltd.Karus Therapeutics Ltd.
-
Systemic Lupus ErythematosusDiscovery
United Kingdom
Karus Therapeutics Ltd.Karus Therapeutics Ltd.
-
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
login
or
view full example data
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
login
or
view full example data
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
login
or
view full example data
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
login
or
view full example data
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
login
or
view full example data
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
login
or
view full example data
Understand key drug designations in just a few clicks with Synapse.
AI Agents Built for Biopharma Breakthroughs
Accelerate discovery. Empower decisions. Transform outcomes.
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free