Last update 23 Sep 2025

DB-1317

Overview

Basic Info

Drug Type
Antibody drug conjugate (ADC)
Synonyms
DB 1317, DB1317
Target
ADAM9
Action
inhibitors
Mechanism
ADAM9 inhibitors(ADAM metallopeptidase domain 9 inhibitors)
Therapeutic Areas
NeoplasmsUrogenital Diseases
Active Indication
Advanced Malignant Solid NeoplasmCastration-Resistant Prostatic CancerSolid tumor
Inactive Indication-
Originator Organization
Duality Biologics (Suzhou) Co., Ltd.Duality Biologics (Suzhou) Co., Ltd.
Active Organization
DualityBio Inc.
Duality Biologics (Suzhou) Co., Ltd.Duality Biologics (Suzhou) Co., Ltd.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Structure/Sequence

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Related

1
Clinical Trials associated with DB-1317
NCT07141706
/ Not yet recruitingPhase 1
A Phase 1a/1b, Multicenter, Open-Label, First-in-Human Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of DB-1317 in Participants With Selected Advanced/Metastatic Solid Tumors
100 Clinical Results associated with DB-1317
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100 Translational Medicine associated with DB-1317
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100 Patents (Medical) associated with DB-1317
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100 Deals associated with DB-1317
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 1
United States
DualityBio Inc.
01 Sep 2025
Advanced Malignant Solid NeoplasmPhase 1
Australia
DualityBio Inc.
01 Sep 2025
Castration-Resistant Prostatic CancerPhase 1
United States
DualityBio Inc.
01 Sep 2025
Castration-Resistant Prostatic CancerPhase 1
Australia
DualityBio Inc.
01 Sep 2025
Solid tumorPreclinical
China
Duality Biologics (Suzhou) Co., Ltd.Duality Biologics (Suzhou) Co., Ltd.
27 May 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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