Last update 21 Nov 2024

SHR0532

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Target
KCNJ1
Mechanism
KCNJ1 inhibitors(potassium inwardly rectifying channel subfamily J member 1 inhibitors)
Therapeutic Areas
Cardiovascular Diseases
Active Indication-
Inactive Indication
HypertensionHypertension, mild
Originator Organization
Jiangsu Hengrui Pharmaceuticals Co., Ltd.Jiangsu Hengrui Pharmaceuticals Co., Ltd.
Active Organization-
Inactive Organization
Jiangsu Hengrui Pharmaceuticals Co., Ltd.Jiangsu Hengrui Pharmaceuticals Co., Ltd.
Drug Highest PhasePendingPhase 1
First Approval Date-
RegulationSpecial Review Project (CN)
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Related

4
Clinical Trials associated with SHR0532
NCT03971929 / CompletedPhase 1
A Phase I, Randomized, Double-Blind, Placebo-hydrochlorothiazide Parallel Controlled, Multiple-Ascending Dose Study to Evaluate the Safety, Efficacy of SHR 0532 Oral Tablets in Mild Hypertension Subjects
CTR20191054 / CompletedPhase 1
多次服SHR0532片在轻度高血压患者的安全性和有效性研究—随机、双盲、剂量递增、安慰剂和氢氯噻嗪平行对照Ⅰ期试验
[Translation] Safety and efficacy of multiple doses of SHR0532 tablets in patients with mild hypertension: a randomized, double-blind, dose-escalation, placebo- and hydrochlorothiazide-controlled phase I trial
CTR20180819 / CompletedPhase 1
健康受试者中单次给予SHR0532片的安全耐受性和药代动力学研究—随机、双盲、剂量递增、安慰剂平行对照Ⅰ期临床试验
[Translation] A randomized, double-blind, dose-escalation, placebo-controlled phase I clinical trial of a single dose of SHR0532 tablets in healthy subjects: safety, tolerability and pharmacokinetics
100 Clinical Results associated with SHR0532
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100 Translational Medicine associated with SHR0532
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100 Patents (Medical) associated with SHR0532
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100 Deals associated with SHR0532
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hypertension, mildPhase 1
CN
Jiangsu Hengrui Pharmaceuticals Co., Ltd.Jiangsu Hengrui Pharmaceuticals Co., Ltd.
25 Jul 2019
HypertensionPhase 1-
Jiangsu Hengrui Pharmaceuticals Co., Ltd.Jiangsu Hengrui Pharmaceuticals Co., Ltd.
24 Aug 2018
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Clinical Result

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Approval

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Regulation

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