Last update 04 Apr 2026

ALN-CFB

Overview

Basic Info

Drug Type
siRNA
Synonyms
ALN CFB
Target
C5
Action
inhibitors
Mechanism
C5 inhibitors(Complement C5 inhibitors)
Therapeutic Areas
Hemic and Lymphatic DiseasesOther Diseases
Active Indication
Hemoglobinuria, Paroxysmal
Inactive Indication-
Originator Organization
Regeneron Pharmaceuticals, Inc.Regeneron Pharmaceuticals, Inc.
Active Organization
Regeneron Pharmaceuticals, Inc.Regeneron Pharmaceuticals, Inc.Alnylam Pharmaceuticals, Inc.Alnylam Pharmaceuticals, Inc.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1/2
First Approval Date-
Regulation-
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Structure/Sequence

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Related

1
Clinical Trials associated with ALN-CFB
NCT07187401
/ RecruitingPhase 1/2
A Randomized, Double-Blind, Placebo-Controlled, First-In-Human Study of the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ALN-CFB, an Investigational siRNA Therapeutic Against Complement Factor B, in Participants With Paroxysmal Nocturnal Hemoglobinuria and Persistent Anemia on Approved C5-Inhibitor Therapy
100 Clinical Results associated with ALN-CFB
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100 Translational Medicine associated with ALN-CFB
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100 Patents (Medical) associated with ALN-CFB
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100 Deals associated with ALN-CFB
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hemoglobinuria, ParoxysmalPhase 2-
Alnylam Pharmaceuticals, Inc.Alnylam Pharmaceuticals, Inc.
13 Oct 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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