Last update 21 Nov 2024

SGN-ALPV

Overview

Basic Info

Drug Type
Antibody drug conjugate (ADC)
Synonyms
Target
ALPP x ALPPL2 x Tubulin
Mechanism
ALPP inhibitors(alkaline phosphatase, placental inhibitors), ALPPL2 inhibitors(alkaline phosphatase, germ cell inhibitors), Tubulin inhibitors
Therapeutic Areas
NeoplasmsDigestive System DisordersEndocrinology and Metabolic Disease+ [2]
Active Indication-
Inactive Indication
Advanced Malignant Solid NeoplasmEndometrial CarcinomaGastroesophageal junction adenocarcinoma+ [4]
Originator Organization
Seagen Inc.Seagen Inc.
Active Organization-
Inactive Organization
Seagen Inc.Seagen Inc.
Drug Highest PhaseDiscontinuedPhase 1
First Approval Date-
Regulation-
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Structure

Molecular FormulaC39H67N5O7
InChIKeyDASWEROEPLKSEI-UIJRFTGLSA-N
CAS Registry474645-27-7
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Related

1
Clinical Trials associated with SGN-ALPV
NCT05229900 / TerminatedPhase 1
A Phase 1 Study of SGN-ALPV in Advanced Solid Tumors
100 Clinical Results associated with SGN-ALPV
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100 Translational Medicine associated with SGN-ALPV
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100 Patents (Medical) associated with SGN-ALPV
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100 Deals associated with SGN-ALPV
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Endometrial CarcinomaPhase 1
US
Seagen Inc.Seagen Inc.
21 Apr 2022
Endometrial CarcinomaPhase 1
SE
Seagen Inc.Seagen Inc.
21 Apr 2022
Endometrial CarcinomaPhase 1
CA
Seagen Inc.Seagen Inc.
21 Apr 2022
Endometrial CarcinomaPhase 1
ES
Seagen Inc.Seagen Inc.
21 Apr 2022
Endometrial CarcinomaPhase 1
GB
Seagen Inc.Seagen Inc.
21 Apr 2022
Ovarian CancerPhase 1
US
Seagen Inc.Seagen Inc.
21 Apr 2022
Ovarian CancerPhase 1
SE
Seagen Inc.Seagen Inc.
21 Apr 2022
Ovarian CancerPhase 1
CA
Seagen Inc.Seagen Inc.
21 Apr 2022
Ovarian CancerPhase 1
ES
Seagen Inc.Seagen Inc.
21 Apr 2022
Ovarian CancerPhase 1
GB
Seagen Inc.Seagen Inc.
21 Apr 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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