Last update 23 Jan 2025

Allogeneic anti-IL3RA｜NKG2D CAR-T (Tianjin First Center Hospital)

Overview

Basic Info

Drug Type
Universal CAR-T
Synonyms-
Target
CD123 x NKG2D
Mechanism
CD123 inhibitors(Interleukin-3 receptor subunit alpha inhibitors), NKG2D antagonists(NKG2-D type II integral membrane protein antagonists)
Therapeutic Areas
NeoplasmsHemic and Lymphatic Diseases
Active Indication
Acute Myeloid Leukemia
Inactive Indication-
Originator Organization
Tianjin First Center HospitalTianjin First Center Hospital
Active Organization
Tianjin First Center HospitalTianjin First Center Hospital
Inactive Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

3
Clinical Trials associated with Allogeneic anti-IL3RA｜NKG2D CAR-T (Tianjin First Center Hospital)
ChiCTR1900022058
/ SuspendedEarly Phase 1IIT
CD123 chimeric antigen receptor T cells (CART) therapy for relapse or refractory Blastic plasmacytoid dendritic cell neoplasm
ChiCTR1800020083
/ RecruitingPhase 1IIT
Donor-derived Anti-CD123-CART Cells for relapse AML After Allo-HSCT
ChiCTR1800017843
/ RecruitingNot ApplicableIIT
A Clinical Research of CD123-Targeted CAR-T in CD123 positive refractory or relapsed Myeloid leukemia
100 Clinical Results associated with Allogeneic anti-IL3RA｜NKG2D CAR-T (Tianjin First Center Hospital)
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100 Translational Medicine associated with Allogeneic anti-IL3RA｜NKG2D CAR-T (Tianjin First Center Hospital)
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100 Patents (Medical) associated with Allogeneic anti-IL3RA｜NKG2D CAR-T (Tianjin First Center Hospital)
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100 Deals associated with Allogeneic anti-IL3RA｜NKG2D CAR-T (Tianjin First Center Hospital)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute Myeloid LeukemiaPhase 1-
Tianjin First Center HospitalTianjin First Center Hospital
-
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Clinical Result

Indication
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Approval

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Regulation

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