Delving into the Latest Updates on Guamecycline Hydrochloride with Synapse

Overview

Basic Info

Drug Type

Small molecule drug

Synonyms-

Target

30S subunit

Mechanism

30S subunit inhibitors(30S ribosomal subunit inhibitors)

Therapeutic Areas

Infectious Diseases

Active Indication

Bacterial Infections

Inactive Indication-

Originator Organization-

Active Organization-

Inactive Organization-

Drug Highest PhaseApproved

First Approval Date-

Regulation-

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Structure

Molecular FormulaC29H40Cl2N8O8

InChIKeySNUNMHCZVZIEMV-KGHBUBBXSA-N

CAS Registry13040-98-7

Tetracycline-HCl (I-HCl) [64-75-5] periodically injected s.c., increased the virulence of Y and M forms of C. albicans in endoperitoneal infection in mice but not in rabbits.No significant difference in mortality rate between mice with the Y or M form was observed although the mean survival time for mice with the M form was longer.The effects of I were dose-dependent.The mortality rate for mice with C. albicans given different tetracyclines was: deoxytetracycline-HCl [51025-87-7] > tetracycline-HCl > guamecycline-HCl [13040-98-7].

21 Nov 1972·Minerva medicaQ4 · MEDICINE

[Guamecycline in the treatment of acute pneumopathies. Clinical research and comparison with other tetracyclines].

Q4 · MEDICINE

Article

Author: Bocarnea, C ; Duminica, A

01 Dec 1969·Scandinavian Journal of Infectious Diseases

Electron Microscopical Appearance of Human Bronchial Epithelium after Long-Term Treatment with Guamecycline by Aerosol Route

Article

Author: Ruozi, Piero ; Pellegrini, Rinaldo

(1969). Electron Microscopical Appearance of Human Bronchial Epithelium after Long-Term Treatment with Guamecycline by Aerosol Route. Scandinavian Journal of Infectious Diseases: Vol. 1, No. 3, pp. 217-218.

100 Deals associated with Guamecycline Hydrochloride

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