Last update 10 Jan 2026

Singletine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
DC-291407, DC-407, DC407
Target
DPP-4
Action
inhibitors
Mechanism
DPP-4 inhibitors(Dipeptidyl peptidase IV inhibitors)
Therapeutic Areas
Digestive System DisordersEndocrinology and Metabolic Disease
Active Indication
Diabetes Mellitus, Type 2Fatty Liver
Inactive Indication-
Originator Organization
Cisen Pharmaceutical Ltd.Cisen Pharmaceutical Ltd.
Active Organization
Cisen Pharmaceutical Ltd.Cisen Pharmaceutical Ltd.Shanghai Institute of Materia Medica Chinese Academy of SciShanghai Institute of Materia Medica Chinese Academy of Sci
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1/2
First Approval Date-
RegulationSpecial Review Project (China)
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Structure/Sequence

Molecular FormulaC21H21N5O3S
InChIKeyXKMHHZMODVVEIO-OAHLLOKOSA-N
CAS Registry1442081-72-2

Related

2
Clinical Trials associated with Singletine
CTR20221874
/ CompletedPhase 1/2
多中心、随机、双盲、安慰剂对照评价口服欣格列汀片中国2型糖尿病合并脂肪性肝病患者中的有效性和安全性Ib/II期临床探索性研究
[Translation] A multicenter, randomized, double-blind, placebo-controlled phase Ib/II clinical exploratory study to evaluate the efficacy and safety of oral sinagliflozin tablets in Chinese patients with type 2 diabetes and fatty liver disease
NCT06160401
/ CompletedPhase 1
Safety, Tolerability and Pharmacokinetic Characteristics of Singletine(DC407) in Healthy Adult Subjects After Single and Multiple Doses: a Single-center, Randomized, Double-blind, Placebo-controlled, Phase 1 Trial
100 Clinical Results associated with Singletine
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100 Translational Medicine associated with Singletine
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100 Patents (Medical) associated with Singletine
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100 Deals associated with Singletine
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetes Mellitus, Type 2Phase 2
China
Shanghai Institute of Materia Medica Chinese Academy of SciShanghai Institute of Materia Medica Chinese Academy of Sci
25 Jul 2022
Diabetes Mellitus, Type 2Phase 2
China
Cisen Pharmaceutical Ltd.Cisen Pharmaceutical Ltd.
25 Jul 2022
Fatty LiverPhase 2
China
Cisen Pharmaceutical Ltd.Cisen Pharmaceutical Ltd.
25 Jul 2022
Fatty LiverPhase 2
China
Shanghai Institute of Materia Medica Chinese Academy of SciShanghai Institute of Materia Medica Chinese Academy of Sci
25 Jul 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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