Last update 13 Dec 2025

DNX-514

Overview

Basic Info

Drug Type
Single-chain FV antibody fragment
Synonyms
DNX-514
Target
TNF
Action
inhibitors
Mechanism
TNF inhibitors(Tumor necrosis factor inhibitors)
Therapeutic Areas
Immune System DiseasesInfectious DiseasesDigestive System Disorders+ [2]
Active Indication-
Inactive Indication
Ankylosing SpondylitisArthritis, PsoriaticColitis, Ulcerative+ [4]
Originator Organization
DNX Biopharmaceuticals, Inc.DNX Biopharmaceuticals, Inc.
Active Organization-
Inactive Organization
DNX Biopharmaceuticals, Inc.DNX Biopharmaceuticals, Inc.
License Organization-
Drug Highest PhaseDiscontinuedPreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with DNX-514
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100 Translational Medicine associated with DNX-514
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100 Patents (Medical) associated with DNX-514
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100 Deals associated with DNX-514
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Ankylosing SpondylitisPreclinical
United States
DNX Biopharmaceuticals, Inc.DNX Biopharmaceuticals, Inc.
31 Aug 2022
Arthritis, PsoriaticPreclinical
United States
DNX Biopharmaceuticals, Inc.DNX Biopharmaceuticals, Inc.
31 Aug 2022
Colitis, UlcerativePreclinical
United States
DNX Biopharmaceuticals, Inc.DNX Biopharmaceuticals, Inc.
31 Aug 2022
Crohn DiseasePreclinical
United States
DNX Biopharmaceuticals, Inc.DNX Biopharmaceuticals, Inc.
31 Aug 2022
Juvenile Idiopathic ArthritisPreclinical
United States
DNX Biopharmaceuticals, Inc.DNX Biopharmaceuticals, Inc.
31 Aug 2022
Plaque psoriasisPreclinical
United States
DNX Biopharmaceuticals, Inc.DNX Biopharmaceuticals, Inc.
31 Aug 2022
Rheumatoid ArthritisPreclinical
United States
DNX Biopharmaceuticals, Inc.DNX Biopharmaceuticals, Inc.
31 Aug 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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