Last update 08 May 2025

TMX-1160

Overview

Basic Info

Drug Type
Proteolysis-targeting chimeras (PROTAC)
Synonyms-
Target
CDK2 x CDK4 x CDK5 x CDK6
Action
inhibitors
Mechanism
CDK2 inhibitors(Cyclin-dependent kinase 2 inhibitors), CDK4 inhibitors(Cyclin-dependent kinase 4 inhibitors), CDK5 inhibitors(Cyclin-dependent kinase 5 inhibitors)
+ [1]
Therapeutic Areas
NeoplasmsEndocrinology and Metabolic DiseaseUrogenital Diseases
Active Indication-
Inactive Indication
Ovarian Cancer
Originator Organization
Dana-Farber Cancer Institute, Inc.Dana-Farber Cancer Institute, Inc.Harvard Medical SchoolHarvard Medical School
Active Organization-
Inactive Organization
Dana-Farber Cancer Institute, Inc.Dana-Farber Cancer Institute, Inc.Harvard Medical SchoolHarvard Medical School
License Organization-
Drug Highest PhasePendingPreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC40H47BrFN9O9S
InChIKeyRVBRYNIJOYPZIA-UHFFFAOYSA-N
CAS Registry-

Related

100 Clinical Results associated with TMX-1160
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100 Translational Medicine associated with TMX-1160
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100 Patents (Medical) associated with TMX-1160
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100 Deals associated with TMX-1160
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Ovarian CancerPreclinical
United States
Dana-Farber Cancer Institute, Inc.Dana-Farber Cancer Institute, Inc.
03 Jun 2020
Ovarian CancerPreclinical
United States
Harvard Medical SchoolHarvard Medical School
03 Jun 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Approval

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Regulation

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