Last update 08 May 2025

LEAD-462

Overview

Basic Info

Drug Type
Bispecific antibody
Synonyms
Target
TAA x TNFR
Action
agonists, inhibitors, stimulants
Mechanism
TNFR agonists(Tumor necrosis factor receptor agonists), Tumor-associated antigen inhibitors(Tumor-associated antigen inhibitors), ADCC(Antibody-dependent cell-mediated cytotoxicity (ADCC) effects)
+ [1]
Therapeutic Areas
NeoplasmsDigestive System DisordersRespiratory Diseases+ [2]
Active Indication
Breast CancerColorectal CancerKidney Neoplasms+ [5]
Inactive Indication-
Originator Organization
LeadArtis SLLeadArtis SL
Active Organization
LeadArtis SLLeadArtis SL
Inactive Organization-
License Organization-
Drug Highest PhaseDiscovery
First Approval Date-
Regulation-

Related

100 Clinical Results associated with LEAD-462
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100 Translational Medicine associated with LEAD-462
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100 Patents (Medical) associated with LEAD-462
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100 Deals associated with LEAD-462
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Breast CancerDiscovery
Spain
LeadArtis SLLeadArtis SL
-
Colorectal CancerDiscovery
Spain
LeadArtis SLLeadArtis SL
-
Kidney NeoplasmsDiscovery
Spain
LeadArtis SLLeadArtis SL
-
Liver CancerDiscovery
Spain
LeadArtis SLLeadArtis SL
-
MelanomaDiscovery
Spain
LeadArtis SLLeadArtis SL
-
Non-Small Cell Lung CancerDiscovery
Spain
LeadArtis SLLeadArtis SL
-
Stomach CancerDiscovery
Spain
LeadArtis SLLeadArtis SL
-
Uterine Cervical CancerDiscovery
Spain
LeadArtis SLLeadArtis SL
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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