Last update 21 Mar 2026

CD19-CAR novel oncolytic vaccinia virus(The Second Affiliated Hospital Zhejiang University)

Overview

Basic Info

Drug Type
CAR-M, Oncolytic virus, CAR-T
Synonyms
Oncolytic Vaccinia VIrus-Delivered Targeted CD19 In Vivo CAR-T/M, RGV-005
Target
CD19
Action
modulators
Mechanism
CD19 modulators(B-lymphocyte antigen CD19 modulators)
Therapeutic Areas
NeoplasmsImmune System DiseasesHemic and Lymphatic Diseases+ [1]
Active Indication
Indolent B-Cell Non-Hodgkin LymphomaMediastinal large B-cell lymphoma
Inactive Indication-
Originator Organization
The Second Affiliated Hospital Zhejiang UniversityThe Second Affiliated Hospital Zhejiang University
Active Organization
The Second Affiliated Hospital Zhejiang UniversityThe Second Affiliated Hospital Zhejiang University
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with CD19-CAR novel oncolytic vaccinia virus(The Second Affiliated Hospital Zhejiang University)
NCT07398963
/ RecruitingPhase 1IIT
Exploratory Study of Oncolytic Vaccinia VIrus-Delivered Targeted CD19 In Vivo CAR-T/M Therapy for Refractory/Relapsed B-Cell Lymphoma
100 Clinical Results associated with CD19-CAR novel oncolytic vaccinia virus(The Second Affiliated Hospital Zhejiang University)
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100 Translational Medicine associated with CD19-CAR novel oncolytic vaccinia virus(The Second Affiliated Hospital Zhejiang University)
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100 Patents (Medical) associated with CD19-CAR novel oncolytic vaccinia virus(The Second Affiliated Hospital Zhejiang University)
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100 Deals associated with CD19-CAR novel oncolytic vaccinia virus(The Second Affiliated Hospital Zhejiang University)
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Indolent B-Cell Non-Hodgkin LymphomaPhase 1
China
The Second Affiliated Hospital Zhejiang UniversityThe Second Affiliated Hospital Zhejiang University
01 Feb 2026
Mediastinal large B-cell lymphomaPhase 1
China
The Second Affiliated Hospital Zhejiang UniversityThe Second Affiliated Hospital Zhejiang University
01 Feb 2026
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Clinical Result

Indication
Phase
Evaluation
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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