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Last update 16 May 2025
68GaNOTA-Anti-MMR-VHH2(Universitair Ziekenhuis Brussel)
Last update 16 May 2025
Overview
Basic Info
Drug Type Radiolabeled antibody, Diagnostic radiopharmaceuticals |
Synonyms- |
Target |
Action inhibitors |
Mechanism CD206 inhibitors(Macrophage mannose receptor 1 inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
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Structure/Sequence
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Related
4
Clinical Trials associated with 68GaNOTA-Anti-MMR-VHH2(Universitair Ziekenhuis Brussel)NCT05933239
A Phase II Study to Evaluate the Imaging Potential of 68GaNOTA-Anti-MMR VHH2 for in Vivo Imaging of MMR-expressing Macrophages by Means of Positron Emission Tomography (PET) in Patients With Non-small Cell Lung Cancer (NSCLC)
EUCTR2021-005575-40-BE
A phase II study to evaluate the imaging potential of 68GaNOTA-Anti-MMR VHH2 for in vivo imaging of MMR-expressing Macrophages by means of Positron Emission Tomography (PET) in patients with non-small cell lung cancer (NSCLC).
NCT04758650
Phase II Study to Evaluate the Clinical Potential of 68GaNOTA-Anti-MMR-VHH2 for in Vivo Imaging of MMR-expressing Macrophages by Means of Positron Emission Tomography (PET) in Oncological Lesions,Cardiovascular Atherosclerosis,Syndrome With Abnormal Immune Activation and sarcoïdosis
100 Clinical Results associated with 68GaNOTA-Anti-MMR-VHH2(Universitair Ziekenhuis Brussel)
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100 Translational Medicine associated with 68GaNOTA-Anti-MMR-VHH2(Universitair Ziekenhuis Brussel)
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100 Patents (Medical) associated with 68GaNOTA-Anti-MMR-VHH2(Universitair Ziekenhuis Brussel)
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100 Deals associated with 68GaNOTA-Anti-MMR-VHH2(Universitair Ziekenhuis Brussel)
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R&D Status
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Locally Advanced Lung Non-Small Cell Carcinoma | Phase 2 | Belgium | 30 Mar 2023 | |
| Atherosclerosis | Phase 2 | Belgium | 26 Jan 2021 | |
| Cardiac sarcoidosis | Phase 2 | Belgium | 26 Jan 2021 | |
| Carotid Stenosis | Phase 2 | Belgium | 26 Jan 2021 | |
| Head and Neck Neoplasms | Phase 2 | Belgium | 26 Jan 2021 | |
| Hodgkin's Lymphoma | Phase 2 | Belgium | 26 Jan 2021 | |
| Lymphohistiocytosis, Hemophagocytic | Phase 2 | Belgium | 26 Jan 2021 | |
| Non-Hodgkin Lymphoma | Phase 2 | Belgium | 26 Jan 2021 | |
| Hormone receptor negative HER2 positive breast cancer | Phase 2 | Belgium | 05 Nov 2019 | |
| Locally Advanced Malignant Solid Neoplasm | Phase 2 | Belgium | 05 Nov 2019 |
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Biosimilar
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Regulation
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