Last update 23 Jan 2025

SZN-8143

Overview

Basic Info

Drug Type
Trispecific antibody
Synonyms
Target
FZD4 x IL-6 x VEGF
Mechanism
FZD4 agonists(frizzled class receptor 4 agonists), IL-6 inhibitors(Interleukin-6 inhibitors), VEGF inhibitors(Vascular endothelial growth factor inhibitors)
Therapeutic Areas
Cardiovascular DiseasesCongenital DisordersEndocrinology and Metabolic Disease+ [2]
Active Indication
Diabetic macular oedemaUveitic Macular EdemaWet age-related macular degeneration
Inactive Indication-
Originator Organization
Surrozen, Inc.Surrozen, Inc.
Active Organization
Surrozen, Inc.Surrozen, Inc.
Inactive Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with SZN-8143
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100 Translational Medicine associated with SZN-8143
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100 Patents (Medical) associated with SZN-8143
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100 Deals associated with SZN-8143
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetic macular oedemaPreclinical
US
Surrozen, Inc.Surrozen, Inc.
01 Nov 2024
Uveitic Macular EdemaPreclinical
US
Surrozen, Inc.Surrozen, Inc.
01 Nov 2024
Wet age-related macular degenerationPreclinical
US
Surrozen, Inc.Surrozen, Inc.
01 Nov 2024
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Clinical Result

Indication
Phase
Evaluation
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Phase
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Approval

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Regulation

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