Last update 06 Dec 2025

Aflibercept biosimilar (IVY Pharma)

Overview

Basic Info

Drug Type
Fc fusion protein, Biosimilar
Synonyms
Aflibercept Biosimilar (Ivy Pharma, Inc.), 阿柏西普生物类似药（Ivy Pharma, Inc.）, IVY-5790
+ [1]
Target
PGF x VEGF-A
Action
inhibitors
Mechanism
PGF inhibitors(Placental Growth Factor inhibitors), VEGF-A inhibitors(Vascular endothelial growth factor A inhibitors)
Therapeutic Areas
Cardiovascular DiseasesCongenital DisordersEndocrinology and Metabolic Disease+ [2]
Active Indication
Diabetic macular oedemaRetinal vein occlusion-related macular edemaWet age-related macular degeneration
Inactive Indication-
Originator Organization
Ivy Pharma, Inc.Ivy Pharma, Inc.
Active Organization
Ivy Pharma, Inc.Ivy Pharma, Inc.
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Structure/Sequence

Related

100 Clinical Results associated with Aflibercept biosimilar (IVY Pharma)
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100 Translational Medicine associated with Aflibercept biosimilar (IVY Pharma)
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100 Patents (Medical) associated with Aflibercept biosimilar (IVY Pharma)
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100 Deals associated with Aflibercept biosimilar (IVY Pharma)
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External Link

KEGGWikiATCDrug Bank
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L01XX44S01LA05
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetic macular oedemaPreclinical
United States
Ivy Pharma, Inc.Ivy Pharma, Inc.
01 Nov 2024
Retinal vein occlusion-related macular edemaPreclinical
United States
Ivy Pharma, Inc.Ivy Pharma, Inc.
01 Nov 2024
Wet age-related macular degenerationPreclinical
United States
Ivy Pharma, Inc.Ivy Pharma, Inc.
01 Nov 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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